• 0 Posts
  • 4 Comments
Joined 1 year ago
Cake day: June 20th, 2023
  • klenow@kbin.socialtoScience@kbin.social•Meat allergy from tick bites is on the rise—and US doctors are in the dark
    4·
    1 year ago

    I work in drug development, and have done a lot of work in topical drug development, specifically for skin diseases. Psoriasis gets most of the attention, but there’s a lot of work being done on other skin diseases, as well

    “Eczema” is kind of a catch-all term for a group of diseases, which is one of the reasons treatment is so difficult. One kind is often mistaken for (or even indistinguishable from) another. The most common, though, is atopic dermatitis (which is hilarious when you look up the etymology).

    So that said… Have you tried JAK inhibitors? Ruxolitinib is one of the best ones, formulated as a cream called Opzelura. It’s at least good for flare ups.

    Unfortunately, there aren’t really any good drugs for preventing it. If you want company on that one, talk to the asthma community.

    But… There is work being done. I’ve worked on it. I’ve had companies spend millions on the work. I haven’t seen anything very promising, but maybe you can take some comfort that there are frustrated scientists working on it, and pharma companies poised to take all of your money once something is found.

  • klenow@kbin.socialtoDungeons and Dragons@lemmy.world•DMs, what are your favorite parts of running this game? Players, what are yours?
    3·
    1 year ago

    DM here. The biggest thing for me is when the players get emotionally engaged to the story and the beats. They fell actual hatred for the BBEG. They get so excited about a reveal that they all can’t talk for a minute. Something happens in game, and half the players are having a chat in the Discord in character, outside of game time. The reactions from the players are so rewarding.

    The next best is when they come up with a solution to a problem in the game that I hadn’t even considered. It’s kind of fun to have to just say “OK. Hang on a minute. I was totally not prepared for y’all to try that, so I’m going to need to figure out what they impact of that is.” The players always get really excited about that; I think they love to stump me.