Pure conjectural or anecdotal but it is my intuition that there is something to it
EDIT: My running theory is related to hormesis or tolerance where the body produces an opposite effect to the ligand to maintain homeostasis and there is not a sufficient dose of the exogenous drug taken to override the body’s compensatory reaction
So even tho caffeine is a stimulant (adenosine antagonist) it actually causes the body to produce the opposite reaction, causing the reverse effect of making you sleepy
Different organisms react differently to the same chemical substances. There’s a study linking ADHD and paradoxical reaction to stimulants:
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC3163785/
As I’m writing this reply, I have not yet been able to find any other studies that delve deeper into the matter, but it seems like it’s indeed a known phenomena.
Yup. I used to be able to chug a monster and go to bed. Then I got medicated and I can’t do that anymore lol.
Can confirm. The first line of speed gets me relaxed.
My son is ADHD and autistic and caffeine calms him down. Sometimes when he misses his meds we will give him some coffee or soda to get him through to his next dose.