The Elitzur–Vaidman bomb-tester is a quantum mechanics thought experiment that uses interaction-free measurements to verify that a bomb is functional without having to detonate it. It was conceived in 1993 by Avshalom Elitzur and Lev Vaidman. Since their publication, real-world experiments have confirmed that their theoretical method works as predicted.
Observation does not require a human observer - the extreme complexity of quantum mechanics remain even without any creature involved.
Even accurately modeling basic chemical reactions without any human interaction takes up more computational power than humanity will ever achieve without a quantum computing.